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. 2017 Jan 12;129(13):1763–1767. doi: 10.1182/blood-2016-10-747170

Table 2.

Univariate Cox proportional hazards models for the risk of bleeding death in the first 30 days

No. included (no. of HD) HR (95% CI) P value
Age, y* 1009 (37) 1.07 (0.89-1.30) .463
PT, s* 837 (33) 1.07 (1.00-1.14) .054
WBC count, 1000 cells/μL* 999 (37) 1.07 (1.03-1.10) <.001
WBC count (grouped)
 High risk (≥20) 129 (16) 5.49 (2.86-10.52) <.001
 Low risk (<20) 870 (21) REF
Platelet count, 1000 cells/μL* 999 (37) 0.91 (0.81-1.02) .107
Platelet count (grouped)
 High risk (<30) 484 (21) 1.41 (0.74-2.71) .297
 Low risk (≥30) 515 (16) REF
Peripheral blast count, 1000 cells/μL* 870 (34) 1.12 (1.05-1.19) <.001
PTT, s* 882 (37) 0.95 (0.79-1.15) .627
Fibrinogen, mg/dL 861 (35) 1.00 (1.00-1.00) .689
Hemoglobin, g/dL* 996 (37) 0.54 (0.10-2.83) .464
Creatinine clearance, mL/min* 869 (36) 0.96 (0.86-1.07) .495
ECOG performance status
 Poor (3-4) 56 (5) 2.76 (1.07-7.08) .035
 Good (0-2) 939 (32) REF
FAB classification
 M3v 125 (8) 2.28 (0.99-5.29) .054
 M3 592 (17) REF

Boldface indicates statistically significant results.

REF, reference level.

*

HR in terms of 10 unit increase.