Fig. 2.

Effect of MMF on renal structure in postischemic and sham-operated rats on high-salt diet. A: representative picosirius red-stained sections showing fibrosis (black arrows) through the renal outer medulla are shown from sham-operated (left), I/R + vehicle (middle), and I/R + MMF (right) athymic and euthymic rats. Magnification is shown. B: quantification of interstitial fibrosis (%area) in both cortex and medulla based on the scoring of picosirius red staining. Data are means ± SE. P < 0.05, injury vs. sham group (*) and MMF vs. vehicle ($) using ANOVA and Student-Neuman-Keuls post hoc test (n = 5–8 animals/group).