Skip to main content
. 2016 Nov 28;6(3):311–316. doi: 10.1242/bio.021410

Fig. 5.

Fig. 5.

miRNA-29c inhibitors attenuated the effect of parecoxib on cell proliferation of GBM cells. (A) miRNA-29c level was determined by RT-qPCR. U343 cells were transfected with NC miRNA, miRNA-29c mimics or miRNA-29c inhibitors for 24 h. Mean±s.d., n=3, *P<0.05, **P<0.01 compared with U343 cells transfected with NC miRNA. (B) The relative cell viability of U343 cells was determined by MTT assay. U343 cells were transfected with NC miRNA, miRNA-29c mimics or miRNA-29c inhibitors for 24 h, followed by treatment with 0 or 200 μM of parecoxib for another 24 h. Mean±s.d., n=3, *P<0.05 compared with cells treated with NC miRNA and PBS; #P<0.05 compared with cells treated with NC miRNA and 200 μM of parecoxib. (C) The BrdU incorporation of U343 cells was determined by BrdU assay. U343 cells were transfected with NC miRNA, miRNA-29c mimics or miRNA-29c inhibitors for 24 h, followed by treatment with 0 or 200 μM of parecoxib for another 24 h. Mean±s.d., n=3, *P<0.05 compared with cells treated with NC miRNA and 200 μM of parecoxib.