Effect of GBRE supplement on the antioxidant enzymes in the experimental rats. (a) Catalase; (b) Superoxide dismutase; (c) Glutathione peroxidase. C: Control, LD: Low dose of GBRE to naïve rat, HD: High dose of GBRE to naïve rat, DM: Diabetes mellitus-induced rat, Pre-DM-LD: Low dose of GBRE to naïve rat and induced DM, Pre-DM-HD: High dose of GBRE to naïve rat and induced DM; Post-DM-LD: Low dose of GBRE to DM rat, Post-DM-HD: High dose of GBRE to DM rat. The significant difference between the groups (a, d, g = when compared with control group; b, e, h = when compared with DM group; c, f, i = when compared with the drug group) were represented as * (p < 0.05), ** (p < 0.01), and *** (p < 0.001).