. Author manuscript; available in PMC: 2018 Apr 1.

Published in final edited form as: Crit Care Med. 2017 Apr;45(4):623–629. doi: 10.1097/CCM.0000000000002262

Table 3.

Predictors of progression to septic shock: Univariate and multivariate regression modeling

Variable	Univariate Model			Multivariate Model

	OR	95% CI	P-value	OR	95% CI	P-value

Sex (Male)	1.18	(1.02 – 1.37)	0.025	1.18	(1.01 – 1.36)	0.032
Charlson Comorbidity Index	1.17	(1.10 – 1.24)	< 0.001	1.18	(1.11 – 1.26)	< 0.001
# Unique Infection Codes	1.06	(1.03 – 1.09)	< 0.001	1.05	(1.02 – 1.08)	0.003
Time to first antimicrobial	1.08	(1.06 – 1.10)	< 0.001	1.08	(1.06 – 1.10)	< 0.001
Time to First broad-spectrum antimicrobial	1.06	(1.05 – 1.08)	< 0.001	–	–	–