Table 4. Summary of Spearman rank correlation coefficients and corrected permutation test p-values (in parenthesis) for regions with the highest correlation between texture and age in TDC subjects.

	Texture scale	Fine			Medium			Coarse
	Brain regions	Average	StDev	Entropy	Average	StDev	Entropy	Average	StDev	Entropy
Left	Thalamus	−0.20 (1)	−0.04 (1)	−0.47 (0.003)*	−0.36 (0.068)	−0.27 (1)	−0.39 (0.022)*	−0.48 (0.005)*	−0.38 (0.043)*	−0.51 (0.003)*
	Caudate	−0.21 (1)	−0.18 (1)	0.12 (1)	−0.42 (0.005)*	−0.37 (0.043)*	−0.43 (0.008)*	−0.47 (0.003)*	−0.46 (0.005)*	−0.45 (0.003)*
	Pallidum	−0.39 (0.041)*	−0.26 (1)	−0.47 (0.003)*	−0.43 (0.005)*	−0.39 (0.015)*	−0.45 (0.005)*	−0.50 (0.003)*	−0.46 (0.003)*	−0.51 (0.003)*
	Vessel	0.38 (0.030)*	0.26 (1)	−0.30 (0.51)	0.45 (0.003)*	0.15 (1)	−0.46 (0.003)*	0.29 (0.679)	0.14 (1)	−0.26 (1)
Right	Thalamus	−0.18 (1)	0.03 (1)	−0.49 (0.003)*	−0.35 (0.066)	−0.25 (1)	−0.38 (0.034)*	−0.39 (0.010)*	−0.06 (1)	−0.51 (0.003)*
	Caudate	−0.25 (1)	−0.22 (1)	0.16 (1)	−0.42 (0.008)*	−0.37 (0.036)*	−0.42 (0.010)*	−0.42 (0.003)*	−0.36 (0.047)*	−0.04 (1)
	Pallidum	−0.37 (0.041)*	−0.25 (1)	−0.45 (0.003)*	−0.41 (0.015)*	−0.36 (0.041)*	−0.43 (0.005)*	−0.39 (0.013)*	−0.36 (0.045)*	−0.41 (0.015)*
	Vessel	0.40 (0.017)*	0.32 (0.221)	−0.12 (1)	0.42 (0.003)*	0.25 (1)	−0.27 (1)	0.25 (1)	0.19 (1)	−0.15 (1)

Significant features (p < 0.05) are represented by a ‘*’ symbol. Correlation coefficients with absolute ρ > 0.4 are highlighted using bold font.