Table 2.
Comparison with prior IO-Therapy studies
| Spierer et al12 (2010) |
Erbagci et al13 (2015) |
Our study | |
|---|---|---|---|
| Study design | No control group | No control group | Clinical trial with patching control group |
| Sample size | 24 | 14 | 19 IO vs 15 Patch |
| Age at treatment (years) | 4–7.8 | 4.5–10 | 3–8 |
| Patients characteristics | Moderate amblyopia, previously treated or untreated | Moderate and severe amblyopia, previously untreated, no optical correction adaptation period | Moderate amblyopia, previously untreated, optical correction adapted, |
| IO-Therapy glasses occlusion setting | 40 seconds on and 20 seconds off | 30 seconds on and 30 seconds off | 30 seconds on and 30 seconds off |
| Daily IO-Therapy hours | At least 8 hours | 4–12 hours | 4 hours |
| Reported follow-up period (months) | 1.5, 3, 4.5, 6, 9 | 3 to 7 (mean 4.0±1.2) | 3 |
| Visual acuity improvement (logMAR) | 0.16±0.3 (at 3-months) | 0.3±0.2 | 0.15±0.12 |