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. 2017 Mar 31;7:45628. doi: 10.1038/srep45628

Table 3. Effect of PG2 on CRP, ESR, IL-6, IL-1β, TNF-σ, and S100B in patients with acute spontaneous intracerebral hemorrhage.

Variable CG (%) (N = 31) TG (%) (N = 30) p-valuea
CRP (mg/L)
 B 0.7 ± 0.7 1.2 ± 3.2 0.9
 D4 1.8 ± 2.7 2.3 ± 4.2 0.9
 D7 1.9 ± 3.3 1.8 ± 2.8 0.9
 D14 1.2 ± 3.4 1.2 ± 2.3 0.9
 D4-B 1.1 ± 2.6 1.1 ± 3.8 1.0
 D7-B 1.2 ± 3.2 0.6 ± 2.6 0.6
 D14-B 0.5 ± 3.0 0.1 ± 1.9 0.8
ESR (mm/h)
 B 12.8 ± 9.7 14.9 ± 23.6 1.0
 D4 18.0 ± 10.5 19.2 ± 26.1 0.9
 D7 20.6 ± 13.1 23.0 ± 27.5 0.8
 D14 22.4 ± 18.9 24.3 ± 26.4 0.9
 D4-B 5.2 ± 7.6 4.3 ± 8.4 0.8
 D7-B 7.8 ± 9.8 8.1 ± 13.1 0.9
 D14-B 9.7 ± 13.7 9.3 ± 13.1 0.9
IL-6 (pg/ml)
 B 2.2 ± 3.37 2.2 ± 1.8 1.0
 D4 1.9 ± 3.01 3.6 ± 5.9 0.9
 D7 7.3 ± 30.2 2.4 ± 2.6 0.8
 D14 1.5 ± 2.2 1.9 ± 2.7 0.9
 D4-B −0.3 ± 2.2 1.4 ± 6.2 0.7
 D7-B 5.1 ± 30.4 0.2 ± 2.5 0.6
 D14-B −0.7 ± 2.9 −0.3 ± 2.5 0.8
IL-1β (pg/ml)
 B 1.9 ± 1.7 2.7 ± 2.7 0.9
 D4 2.0 ± 1.8 2.3 ± 1.9 0.9
 D7 2.0 ± 1.7 2.2 ± 1.8 0.8
 D14 2.1 ± 2.0 1.9 ± 1.5 0.9
 D4-B 0.1 ± 1.4 −0.4 ± 2.7 0.7
 D7-B 0.1 ± 1.5 −0.5 ± 2.8 0.6
 D14-B 0.2 ± 1.6 −0.9 ± 2.4 0.2
TNF-α (pg/ml)
 B 12.2 ± 29.4 13.3 ± 41.6 1.0
 D4 12.8 ± 31.2 11.6 ± 33.2 0.9
 D7 24.9 ± 57.8 8.0 ± 20.1 0.5
 D14 25.2 ± 53.2 4.9 ± 7.4 0.2
 D4-B 0.6 ± 3.2 −1.7 ± 10.1 0.7
 D7-B 12.7 ± 49.0 −5.4 ± 22.9 0.4
 D14-B 13.1 ± 39.9 −8.5 ± 36.6 0.2
S100B (pg/ml)
 B 79.6 ± 143.0 57.2 ± 62.7 0.9
 D4 48.6 ± 55.0 40.4 ± 66.3 0.9
 D7 60.1 ± 79.2 35.8 ± 46.7 0.5
 D14 43.1 ± 61.0 34.5 ± 51.0 0.9
 D4-B −31.0 ± 137.2 −16.8 ± 87.0 0.8
 D7-B −19.5 ± 112.2 −21.4 ± 80.9 0.9
 D14-B −36.5 ± 146.4 −22.7 ± 83.2 0.8

Data presented as mean ± standard deviations. CG: control group; TG: treatment group; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; IL-6: interleukin-6; IL-1β: interleukin-1β; TNF-α: tumor necrosis factor-α; S100B: S100B protein; B: baseline; D4: 4th day after intravenous injection of PG2; D7: 7th day after intravenous injection of PG2; D14: 14th day after intravenous injection of PG2; independent test for continuous data. acorrected p-value for multiple testing.