Table 5.
The association between rs174547 and fat distribution in women (N = 586)
| Indicators | T/T | T/C | C/C | P valuea | Effect (SD) | P valueb | Effect (SD) | P valuec | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | Addictive | Dominant | Recessive | Addictive | Dominant | Recessive | Addictive | Dominant | Recessive | |||
| BMI (kg/m2) | 23.60 (3.28) | 23.66 (3.06) | 22.64 (3.30) | 0.026 | 0.274 | 0.006** | - | - | - | - | - | - | - | - |
| Weight (kg) | 57.72 (8.75) | 58.11 (8.15) | 55.11 (8.59) | 0.029* | 0.424 | 0.002** | −0.46 (0.42) | 0.733 | 0.71 | 0.281 | - | - | - | - |
| Waist circumference (cm) | 80.54 (9.08) | 80.74 (8.45) | 77.71 (9.36) | 0.017* | 0.235 | 0.003** | −0.47 (0.43) | 0.337 | 0.585 | 0.271 | - | - | - | - |
| Hip circumference (cm) | 92.02 (6.00) | 91.89 (5.35) | 90.88 (5.94) | 0.129 | 0.327 | 0.111 | 0.37 (0.34) | 0.63 | 0.859 | 0.27 | - | - | - | - |
| Waist-to-height ratio | 0.52 (0.06) | 0.52 (0.06) | 0.50 (0.06) | 0.023* | 0.181 | 0.011* | −0.002 (0.002) | 0.402 | 0.367 | 0.656 | - | - | - | - |
| Waist-to-hip ratio | 0.87 (0.06) | 0.88 (0.06) | 0.85 (0.07) | 0.018* | 0.357 | 0.001** | −0.01 (0.01) | 0.184 | 0.696 | 0.049* | - | - | - | - |
| Android fat mass percent | 3.18 (0.80) | 3.12 (0.79) | 2.89 (0.87) | 0.002** | 0.023* | 0.005** | −0.09 (0.04) | 0.052 | 0.039* | 0.286 | −0.09 (0.04) | 0.052 | 0.041* | 0.278 |
| Gynoid fat mass percent | 5.64 (0.90) | 5.59 (0.85) | 5.54 (0.97) | 0.291 | 0.442 | 0.315 | −0.02 (0.07) | 0.922 | 0.766 | 0.856 | 0.02 (0.08) | 0.948 | 0.900 | 0.786 |
| Android/gynoid fat ratio | 0.57 (0.16) | 0.57 (0.16) | 0.53 (0.18) | 0.038* | 0.103 | 0.068 | −0.01 (0.01) | 0.231 | 0.206 | 0.505 | - | - | - | - |
| Total fat mass percent | 32.17 (5.83) | 31.94 (5.73) | 30.07 (6.48) | 0.006** | 0.08 | 0.003** | −0.32 (0.20) | 0.118 | 0.169 | 0.230 | - | - | - | - |
| Limb fat mass percent | 12.80 (2.41) | 12.66 (2.39) | 12.19 (2.39) | 0.040* | 0.165 | 0.037* | −0.10 (0.11) | 0.364 | 0.374 | 0.557 | −0.11 (0.17) | 0.522 | 0.499 | 0.724 |
| Trunk fat mass percent | 18.12 (4.09) | 18.05 (4.08) | 16.66 (4.65) | 0.006** | 0.101 | 0.003** | −0.21 (0.14) | 0.14 | 0.235 | 0.206 | −0.18 (0.14) | 0.185 | 0.299 | 0.240 |
aAdujsted for age; bAdjusted for age, income, smoking, drinking, physical activity and BMI; cAdjusted for age, income, smoking, drinking, physical activity, BMI, and other regional fat (For android fat mass percent, the gynoid fat mass percent was further adjusted, vice versa; for limb fat mass percent, the trunk fat mass percent was further adjusted, vice versa); *P < 0.05, **P < 0.01