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Representative FISH images of BM cells. a The status of MYCN amplification using a dual-color probe. Green signals represent the specific probe for MYCN and red signals stand for centromeric chromosome 2 probes. MYCN signals show more than 30 copies within the nuclei. b The status of 1pLOH using a dual-color probe. Green signals represent the copy numbers at 1q21 and red signals are the specific DNA probe of 1p36. Bars 5 μm
