Table 2.

Gene ontology results of modules detected by jActiveModule in network 1

Module	Size	S A	R A	Typical GO terms	p-value
1	26	250.39	1	galactose catabolic process via UDP-galactose	3.42×10−04
				glycolytic fermentation to ethanol	2.72×10−03
				amino acid catabolic process to alcohol via Ehrlich pathway	1.25×10−02
2	5	58.21	0	response to heat	2.16×10−03
3	16	270.79	2	galactose catabolic process via UDP-galactose	4.85×10−05
4	18	169.89	2	galactose catabolic process via UDP-galactose	1.15×10−04
				cellular carbohydrate metabolic process	3.27×10−02
5	4	37.05	0	None	Not available

S _A and R _A are the objective functions of active module score and KEGG pathway coverage score, respectively. The values are calculated by the proposed objective functions using the same parameters setting as the proposed algorithm. τ=1.76×10⁻⁴ and R _ratio=0.6