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. 2017 Mar 14;18(Suppl 2):142. doi: 10.1186/s12864-017-3490-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Complex-based methods are robust against batch effects (simulations): Distribution of F-scores for SP, HE, SNET and FSNET in simulated data where batch effects are absent or present based on the simulated complexes (pseudo-complexes) and individual proteins. Note that for SP, the F-scores shown are always based on individual proteins (Abbreviations: Single-Protein t-test, SP; Hypergeometric Enrichment, HE; SubNET, SNET; Fuzzy SNET; FSNET)