Table 1.

Effects on precision and recall for D2.2.301H and D2.2.302H before and following removal of proteins with heavy loadings on the first principal component (PC1 and − PC1 respectively)

	Precision	Recall	F-score	Jaccard
301H (PC1)	1.00	0.30	0.46
301H (-PC1)	1.00	0.35	0.52
301H (TT/-PC1)	0.65	0.23	0.34	0.48
302H (PC1)	0.94	0.32	0.48
302H (-PC1)	0.93	0.43	0.59
302H (TT/-PC1)	0.72	0.30	0.42	0.61

TT refers to the standard t-test while TT/-PC1 are the top n-ranked TT-features (restricted to the number of features in –PC1). The Jaccard coefficient indicates limited overlaps amongst the top TT-features associated with –PC1 features