Skip to main content
. 2017 Mar 31;9:25. doi: 10.1186/s13195-017-0253-y

Fig. 5.

Fig. 5

18F-THK5351 autoradiography competition with R-(–)-deprenyl hydrochloride shows dose-dependent uptake decline. a In vitro autoradiography of the postmortem striatum, prefrontal cortex, and hippocampal brain sections of Alzheimer’s disease (AD) patients and controls showing the reduction of baseline 18F-THK5351 binding after 150 nM and 500 nM R-(–)-deprenyl hydrochloride challenge. b Reduction of percentage of 18F-THK5351 total uptake is greater in the striatum than in the prefrontal cortex and hippocampus