Table 2. Expression rates of mesothelioma markers in non-MPM tumors.
| SKM9-2 antigen | Calretinin | CK5/6 | Podoplanin | WT-1 | Mesothelin | |
|---|---|---|---|---|---|---|
| Lung carcinoma | 0/98 | 23/98 | 41/98 | 13/98 | 0/98 | 44/98 |
| Renal cell carcinoma | 0/10 | 0/10 | 1/10 | 0/10 | 0/10 | 0/10 |
| Gastric adenocarcinoma | 0/10 | 2/10 | 7/10 | 6/10 | 0/10 | 1/10 |
| Colon adenocarcinoma | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 |
| Breast cancer | 0/10 | 1/10 | 2/10 | 0/10 | 1/10 | 0/10 |
| Ovary adenocarcinoma | 0/10 | 0/10 | 7/10 | 1/10 | 3/10 | 6/10 |
| Urothelial carcinoma | 1/10 | 2/10 | 7/10 | 0/10 | 0/10 | 0/10 |
| Carcinosarcoma | 0/10 | 3/10 | 6/10 | 2/10 | 2/10 | 3/10 |
| Liposarcoma | 0/10 | 6/10 | 1/10 | 1/10 | 1/10 | 0/10 |
| Rhabdomyosarcoma | 0/10 | 1/10 | 0/10 | 2/10 | 1/10 | 0/10 |
| Leiomyosarcoma | 1/10 | 1/10 | 0/10 | 2/10 | 0/10 | 0/10 |
| Fibrosarcoma | 0/10 | 2/10 | 0/10 | 0/10 | 1/10 | 0/10 |
| Synovial sarcoma | 0/10 | 2/10 | 2/10 | 5/10 | 1/10 | 2/10 |
| Gastrointestinal stromal tumor (GIST) | 0/9 | 0/9 | 0/9 | 1/9 | 1/9 | 0/9 |
| Ewing’s sarcoma | 0/10 | 1/10 | 0/10 | 2/10 | 0/10 | 0/10 |
| Alveolar soft part sarcoma (ASPS) | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 | 0/10 |
| Solitary fibrous tumor | 0/10 | 0/10 | 0/10 | 3/10 | 0/10 | 0/10 |
| Malignant peripheral nerve sheath tumor (MPNST) | 0/10 | 2/10 | 2/10 | 4/10 | 0/10 | 0/10 |
| Angiosarcoma | 0/10 | 3/10 | 2/10 | 7/10 | 0/10 | 0/10 |
| Chondrosarcoma | 0/10 | 0/10 | 0/9 | 8/10 | 0/7 | 0/10 |
| Osteosarcoma (OS) | 0/10 | 0/10 | 0/10 | 4/10 | 0/10 | 0/10 |
| Epithelioid hemangioendothelioma | 1/6 | 0/6 | 3/6 | 2/6 | 0/6 | 0/6 |
| Epithelioid angiosarcoma | 0/2 | 2/2 | 2/2 | 1/2 | 0/2 | 0/2 |
| Biphasic synovial sarcoma | 0/5 | 4/5 | 4/5 | 2/5 | 0/5 | 4/5 |
| Total | 3/310 | 55/310 | 87/309 | 66/310 | 11/307 | 60/310 |
| Specificity | 99% | 82% | 72% | 79% | 96% | 81% |
Intensity and proportion of staining in tumor cells were evaluated in the entire microscopic field of each specimen. Cases were defined as positive if the proportion score was more than 0. In the immunostaining of calretinin or WT-1, staining in the nucleus, but not the cytoplasm, was considered a positive sample.