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. 2017 Mar 22;23:1413–1420. doi: 10.12659/MSM.899618

Figure 1.

Figure 1

Astragaloside IV decreased LPS-stimulated production of inflammatory cytokines in a murine model of endotoxinemia. (A) Concentration of plasma TNF-α; (B) Concentration of plasma IL-1β. Concentrations of TNF-α and IL-1β in the plasma were detected by ELISA. LPS induced production of TNF-α and IL-1β in the plasma compared to the control group, whereas AS-IV attenuated the increase in a dose-dependent manner (mean ±SEM, n=8/group). * Indicates that p<0.05 when compared to the LPS group. LPS – lipopolysaccharide; LA – low-dose AS-IV; MA – medial-dose AS-IV; HA – high-dose AS-IV; TNF – tumor necrosis factor; IL – interleukin.