Table II.
Association of GPS score with clinicopathological characteristics in patients undergoing hepatectomy.
| Characteristics | Overall (n=72) | GPS=0 (n=49) | GPS=1 (n=16) | GPS=2 (n=7) | P-value |
|---|---|---|---|---|---|
| Age (years) | |||||
| Mean ± SD | 53.26±11.05 | 53.51±11.16 | 49.88±13.00 | 59.29±8.538 | 0.191 |
| Gender | 0.209 | ||||
| Male | 29 | 18 | 6 | 5 | |
| Female | 43 | 31 | 10 | 2 | |
| Child-Pugh class | 0.003 | ||||
| A | 63 | 47 | 12 | 4 | |
| B | 9 | 2 | 4 | 3 | |
| CRP (mg/l) | 8.321±16.33 | 2.34±2.52 | 12.07±10.24 | 41.65±34.88 | <0.001 |
| Albumin (g/l) | 36.99±5.05 | 39.34±3.12 | 32.93±5.31 | 29.90±2.61 | <0.001 |
| HBV status | |||||
| Positive | 34 | 26 | 6 | 2 | 0.324 |
| Negative | 38 | 23 | 10 | 5 | |
| Vascular invasion | 0.234 | ||||
| Yes | 40 | 26 | 8 | 6 | |
| No | 32 | 23 | 8 | 1 | |
| Tumour size (cm) | 0.005 | ||||
| Mean ± SD | 5.82±3.42 | 5.01±3.22 | 7.06±3.37 | 8.71±2.81 | |
| No. of tumours | 0.850 | ||||
| 1 | 55 | 37 | 13 | 5 | |
| ≥2 | 17 | 12 | 3 | 2 | |
| AFP (ng/ml) | |||||
| Mean ± SD | 4,130.0±10,926.52 | 4,645.83±12,107.70 | 3,088.98±7,596.47 | 253.63±5,536.98 | 0.588 |
| ALT (U/l) | |||||
| Mean ± SD | 83.24±166.23 | 60.12±73.20 | 160.81±323.78 | 67.71±39.13 | 0.105 |
| AST (U/l) | |||||
| Mean ± SD | 85.26±153.28 | 63.40±74.93 | 140.48±295.08 | 106.67±51.43 | 0.204 |
| Total bilirubin (µmol/l) | |||||
| Mean ± SD | 24.58±26.41 | 23.96±20.62 | 28.89±46.83 | 21.92±15.63 | 0.816 |
| CA 19–9 (U/l) | 0.824 | ||||
| <37 | 27 | 19 | 5 | 3 | |
| ≥37 | 45 | 30 | 11 | 4 | |
| Ascites | 0.035 | ||||
| Negative | 63 | 44 | 15 | 4 | |
| Positive | 9 | 5 | 1 | 4 | |
| Lymph node metastases | 0.002 | ||||
| Yes | 21 | 8 | 9 | 4 | |
| No | 51 | 41 | 7 | 3 | |
| TNM classification | 0.048 | ||||
| I | 3 | 3 | 0 | 0 | |
| II | 24 | 21 | 3 | 0 | |
| III | 45 | 25 | 13 | 7 |
Bold print indicates statistical significance. CRP, C-reactive protein; HBsAg, hepatitis B surface antigen; AFP, α-fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CA 19–9, carbohydrate antigen 19–9; TNM, tumour-node-metastasis; GPS, Glasgow Prognostic Score.