Table II.

Adverse events occurring in ≥1 patients.

	Level 1 (n=3) Grade				Level 2 (n=3) Grade
Adverse events	1	2	3	4	1	2	3	4
Hematological
Leukopenia			2				2
Neutropenia	1		1	1			1	1
Decreased hemoglobin				3	1		2
Thrombocytopenia	1			2	1		2
AST/ALT elevation	1	1					2
Increased creatinine	1
Nonhematological
Fatigue	1	2
Fever	1
Nausea	2
Vomiting					1
Anorexia	1					1
Malaise	1
Diarrhea		1
Constipation	1				2
Peripheral sensory neuropathy	3				2	1
Muscle pain	1				1		1
Arthralgia	1				1		1
Alopecia	1	1			1	1
Rash						1
Stomatitis		1			1
Dysgeusia	1

AST, aspartate aminotransferase; ALT, alanine aminotransferase.