Table 1.
Demographic information is shown as the mean ± standard deviation. p-Values were derived from Fisher's Exact test for Gender, whereas all other comparisons including Age, Education, Mini-Mental Status Examination (MMSE), and Hamilton Depression Rating Scale (HMD Scale) were derived from one-way analysis of variance. All analyses were considered statistically significant at p < .05.
| HC (n = 24) | PDAR (n = 17) | PDT (n = 15) | p-value | |||
|---|---|---|---|---|---|---|
|
| ||||||
| NC vs PDAR | NC vs PDT | PDAR vs PDT | ||||
| Age (yrs.) | 57.8 ± 7.4 | 59.1 ± 7.4 | 61.7 ± 6.7 | .836 | .236 | .569 |
| Gender (M:F) | 11:13 | 9:8 | 6:9 | .876 | .423 | .724 |
| Education (yrs.) | 15.8 ± 2.4 | 13.9 ± 2.1 | 15.2 ± 3.2 | .068 | .795 | .329 |
| MMSE | 29.6 ± .9 | 29.1 ± 1.2 | 29.7 ± .5 | .257 | .959 | .221 |
| HAM-D Scale | 3.7 ± 2.1 | 7.2 ± 3.3 | 6.9 ± 4.0 | .0003 | .078 | .215 |
| Disease duration (yrs.) | NA. | 3.7 ± 4.6 | 3.5 ± 3.5 | NA | NA | .91 |
| UPDRS III | 1.2 ± 2.6 | 20.8 ± 12.9 | 17.1 ± 9.5 | <.0001 | <.0001 | .27 |
| T/AR | NA. | .18 ± .22 | 2.63 ± 1.77 | NA. | NA. | <.0001 |
| H&Y stage | NA. | 1.7 ± .6 | 1.7 ± .6 | NA. | NA. | .96 |
| LEDD (mg/day) | NA. | 366 ± 229 | 354 ± 282 | NA. | NA. | .88 |
UPDRS = Unified Parkinson's Disease Rating Scale III; T/AR = mean tremor/mean akinetic/rigidity score; LEDD = Levodopa equivalent daily dosage.