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. 2017 Mar 31;12(3):e0174649. doi: 10.1371/journal.pone.0174649

Table 4. Urine Na/K ratio and background factors.

Urine Na/K≥2.5 Urine Na/K<2.5 p-value
n = 56 n = 32
Age 68.0±12.2 71.3±11.6 0.22
Gender male 37 (66.1%) 20 (62.5%) 0.82
Female 19 (33.9%) 12 (37.5%)
Etiology of cirrhosis ALD 15 (26.8%) 7 (21.9%) 0.17
HBV 0 (0.0%) 3 (9.4%)
HCV 31 (55.4%) 16 (50.0%)
Others 10 (17.9%) 6 (18.8%)
Child B 38 (67.9%) 20 (62.5%) 0.65
C 18 (32.1%) 12 (37.5%)
Co-exsisting of HCC 23 (41.1%) 17 (53.1%) 0.37
Furosemide (≦40/ >40mg/day) 47/9 30/2 0.32
Spironolactone (≦50/ >50mg/day) 52/4 31/1 0.64
Albumin (g/dL) 2.5±0.6 2.6±0.4 0.46
Total bilirubin (mg/dL) 1.5±1.0 1.7±1.2 0.34
Serum Creatinine (mg/dL) 1.13±0.97 0.93±0.36 0.26
Serum Na (mEq/L) 138.0±3.3 134.2±5.9 <0.05
eGFR (mg/min/1.73m2) 64.2±28.1 66.1±29.9 0.76
CRP (mg/dL) 0.79±1.02 1.73±1.71 <0.05
Urine Na (mEq/L) 82.5±25.4 39.8±22.4 <0.05
Urine K (mEq/L) 18.7±8.6 30.9±14.0 <0.05
Urine osmolarity (mOsm/L) 363±105 449±138 <0.05
Platelet counts (×104/μL) 10.0±6.5 10.1±4.8 0.94
Prothrombin activity (%) 72.9±17.2 69.4±22.6 0.42

HCV: hepatitis C virus, HBV: hepatitis B virus, ALD: alcoholic liver disease, HCC: hepatocellular carcinoma