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. 2017 Mar 17;6:e21064. doi: 10.7554/eLife.21064

Figure 7. Our model for the role of PCGF6-PRC1.

Figure 7.

(A) Schematic representation for two major modes of gene silencing by PRC1. The first involves PCGF1-PRC1 (PCGF6) and cPRC1 (MEL18/BMI1), which silences developmental genes, and the second involves PCGF6-PRC1 (PCGF6), which silences germ cell-related and meiosis-related genes. (B) Schematic representation of PCGF6-PRC1-mediated regulation of germ cell-related and meiosis-related genes in ESCs and pre-/peri-implatation embryos.

DOI: http://dx.doi.org/10.7554/eLife.21064.016