TABLE 2.
Expression of IFNGR and IFN-γ in bat and human cell linesa
| Cell line and mRNAb | Expression level (crude/normalized no. of reads) forc: |
||
|---|---|---|---|
| Uninfected | wt EBOV | MARV | |
| HepG2 | |||
| IFNGR1 | 135.6/0.411 | 162.5/0.369 | 315.0/0.711 |
| IFNGR2 | 114.3/0.346 | 176.5/0.392 | 351.0/0.778 |
| 293T | |||
| IFNGR1 | 119.5/0.288 | 115.0/0.386 | ND |
| IFNGR2 | 145.0/0.336 | 93.2/0.312 | ND |
| RoNi/7 | |||
| IFNGR* | 40.0/0.266 | 0/NA | 0/NA |
| R06EJ | |||
| IFNGR* | 72.0/0.257 | 0/NA | 0/NA |
| IFN-γ** | 45.0/0.183 | 6.5/0.05 | 37.0/0.301 |
a
Expression was determined by transcriptome analysis. Data are (crude/normalized number of reads); mean values from 2 biological replicates are shown.
b
*, IFNGR type not specified; **, other cell lines tested did not express detectable amounts of IFN-γ mRNA.
c
ND, not determined; NA, not applicable.