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Increased cell death of DRG tissue and general toxicity. A. The cell death of DRG was examined by TUNEL assay. TUNEL-positive cells were green-colored with Alexa 488 and nuclei were blue-colored. The DRG tissue was magnified 40× with a confocal microscope, and the length of the scale bar is 100 μm. B. Body weight of mice every 10 days. The graph shows the means ± SEMs with ***P<0.001, which was analyzed by two-way ANOVA.
