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The IC50 of CDDP in OVCAR3 and SKOV3 cells transfected with miR-490-3p ASO and ABCC2 siRNA or controls
| IC50 (µmol/L) | ASO-ctrl + si-ctrl | miR-490-3p ASO + si-ctrl | miR-490-3p ASO + siR-ABCC2 |
|---|---|---|---|
| OVCAR3 | 9.82 ± 1.67 | 13.64 ± 2.24a | 11.45 ± 1.95b |
| SKOV3 | 4.33 ± 0.73 | 6.97 ± 1.14a | 5.57 ± 1.08b |
P<0.01, ASO-ctrl + si-ctrl group vs miR-490-3p ASO + si-ctrl group;
P<0.01, miR-490-3p ASO + si-ctrl group vs miR-490-3p ASO + siR-ABCC2 group.
