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The IC50 of CDDP in OVCAR3 and SKOV3 cells transfected with miR-490-3p mimics and ABCC2 or controls
| IC50 (µmol/L) | mimics-ctrl + PCMV6 ctrl | miR-490-3p mimics + PCMV6 ctrl | miR-490-3p mimics + PCMV6/ABCC2 |
|---|---|---|---|
| OVCAR3/CDDP | 63.21 ± 11.36 | 38.62 ±6.42a | 49.77 ± 8.35b |
| SKOV3/CDDP | 57.34 ± 10.05 | 34.58 ± 6.21a | 42.18 ± 7.49b |
P<0.01, mimics-ctrl + PCMV6 ctrl group vs miR-490-3p mimics + PCMV6 ctrl group;
P<0.01, miR-490-3p mimics + PCMV6 ctrl vs miR-490-3p mimics + PCMV6/ABCC2 group.
