Table 2.
CD34+ | CD34+/CD133+ | CD34+/CXCR4+ | CD34+/CD133+/CXCR4+ | |||||
---|---|---|---|---|---|---|---|---|
Δ* | P value† | Δ* | P value† | Δ* | P value† | Δ* | P value† | |
Unadjusted | −5.2% | 3.9 × 10−4 | −8.6% | 7.2 × 10−7 | −5.3% | 0.002 | −9.3% | 1.1 × 10−5 |
Adjusted model 1‡ |
−5.5% | 4.4 × 10−4 | −8.3% | 4.7 × 10−6 | −5.8% | 0.002 | −9.0% | 6.8 × 10−5 |
Adjusted model 2§ |
−5.5% | 0.001 | −7.7% | 2.5 × 10−5 | −6.0% | 0.002 | −8.6% | 1.8 × 10−4 |
Δ represents the % change in PCs per 10% decrease in LTL. Linear regression analyses were performed with log base of 2 transformations of LTL and PCs, with PCs as outcomes. ∆ was calculated as (2β − 1) × 0.10.
P values were derived from linear regression models.
Model 1: Adjusted for age, gender, race (white vs non-white), BMI, smoking and previous MI.
Model 2: Adjusted for model 1 + absolute monocyte count. P values remained significant when monocyte count was replaced with total leukocyte, lymphocyte, or granulocyte count.
Abbreviations: LTL: Leukocyte telomere length. PCs: Progenitor Cells.