Table 1.
Non-drinkers |
Light drinkers |
Moderate/Heavy drinkers |
|||||||
---|---|---|---|---|---|---|---|---|---|
Before | After | p-Value | Before | After | p-Value | Before | After | p-Value | |
Number | 8914 | 12,644 | 4448 | ||||||
Sex, male/female | 1894/7020 | 5623/7021 | 4198/250 | ||||||
Age, years | 68.1 (9.1) | 69.6 (9.1) | 65.7 (9.4) | 67.2 (9.4) | 64.6 (8.9) | 66.1 (8.8) | |||
Body weight, kg | 53.9 (9.7) | 54.4 (9.9) | <0.001 | 57.2 (9.9) | 57.8 (10.1) | <0.001 | 62.7 (9.4) | 63.7 (9.7) | <0.001 |
BMI, kg/m2 | 23.4 (3.4) | 23.7 (3.5) | <0.001 | 23.4 (3.2) | 23.7 (3.3) | <0.001 | 23.6 (2.9) | 24.0 (3.0) | <0.001 |
Overweight: BMI ≥25, % | 30.1 | 33.3 | <0.001 | 28.4 | 32.6 | <0.001 | 30.13 | 35.25 | <0.001 |
Hypertension, % | 55.4 | 60.8 | <0.001 | 50.6 | 56.3 | <0.001 | 60.81 | 67.65 | <0.001 |
Smoking, % | 6.5 | 5.5 | <0.001 | 10.8 | 9.4 | <0.001 | 31.4 | 27.5 | <0.001 |
Dyslipidemia, % | 28.9 | 32.7 | <0.001 | 23.6 | 27.45 | <0.001 | 14.0 | 17.6 | <0.001 |
Diabetes, % | 9.4 | 10.4 | <0.001 | 8.0 | 9.29 | <0.001 | 8.8 | 11.0 | <0.001 |
AST, IU/La | 23 (19–26) | 23 (19–27) | <0.001 | 23 (19–27) | 23 (20–27) | <0.001 | 25 (22–30) | 26 (22–31) | <0.001 |
ALT, IU/La | 17 (13–22) | 17 (13–23) | <0.001 | 17 (14–23) | 18 (14–24) | <0.001 | 20 (15–27) | 21 (16–29) | <0.001 |
γ-GTP, IU/La | 18 (14–25) | 18 (14–27) | <0.001 | 21 (16–31) | 22 (16–33) | <0.001 | 40 (27–67) | 42 (27–71) | <0.001 |
Liver dysfunction, % | 9.0 | 11.7 | <0.001 | 12.9 | 15.5 | <0.001 | 41.2 | 44.6 | <0.001 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; BMI, body mass index; γ-GTP, gamma-glutamyl transpeptidase.
Data are mean values (standard deviation) for continuous variables and percentage values for categorical variables, unless otherwise noted.
Reported as median (interquartile range).