Table 4.

Associations of changes in AST, ALT, or γ-GTP and factors among 26,006 participants after the Great East Japan Earthquake.

	Variable	Non-drinkers		Light drinkers		Moderate/Heavy drinkers
		β	p-Value	β	p-Value	β	p-Value
ΔAST	Age, per 1 year	−0.007	0.491	−0.018	0.017	−0.020	0.386
	Women vs. men	−0.79	<0.001	−1.00	<0.001	−2.43	0.005
	Body mass index, per 1 kg/m2	0.19	<0.001	0.13	<0.001	0.13	0.063
	Smoking, yes	−0.98	0.012	−0.35	0.138	0.87	0.047
	Evacuation, yes	0.69	<0.001	0.91	<0.001	−0.60	0.148
ΔALT	Age, per 1 year	−0.18	<0.001	−0.15	<0.001	−0.18	<0.001
	Women vs. men	−3.18	<0.001	−2.39	<0.001	−3.48	<0.001
	Body mass index, per 1 kg/m2	0.54	<0.001	0.47	<0.001	0.49	<0.001
	Smoking, yes	−1.23	0.03	−0.13	0.695	1.08	0.028
	Evacuation, yes	1.49	<0.001	2.17	<0.001	1.39	0.003
Δγ-GTP	Age, per 1 year	−0.11	<0.001	−0.10	<0.001	−0.37	<0.001
	Women vs. men	−2.66	<0.001	−1.85	<0.001	−16.7	<0.001
	Body mass index, per 1 kg/m2	0.26	<0.001	0.04	0.580	0.48	0.111
	Smoking, yes	0.04	0.962	1.67	0.017	9.03	<0.001
	Evacuation, yes	1.79	<0.001	2.53	<0.001	1.38	0.437

Δ, change in variable before and after the Great East Japan Earthquake; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GTP, gamma-glutamyl transpeptidase, β; standardized coefficients beta.

Multiple regression model included changes of AST, ALT, or γ-GTP as dependent variables and the combination of age, sex, body mass index, smoking status, and evacuation as independent variables.