Table 2.
Body weight, plasma lipids, and glucose.
| Rag control | CD4+ STAT4−/− |
CD4+ STAT4+/+ |
CD8+ STAT4−/− |
CD8+ STAT4+/+ |
|
|---|---|---|---|---|---|
| Body weight (g) |
39.3 ± 2.0 | 44.9 ± 3.0 | 38.1 ± 6.3 | 45.4 ± 2.9 | 38.9 ± 5.6 |
| Triglycerides (mg/dL) |
46.1 ± 8.5 | 65.2 ± 13.5 | 111.6 ± 54.5 | 40.7 ± 9.5 | 119.8 ± 79.2 |
| Free FA (mEq/L) |
1.3 ± 0.17 | 0.89 ± 0.25 | 1.15 ± 0.25 | 0.68 ± 0.18∗# | 1.17 ± 0.17 |
| Cholesterol (mg/dL) |
170.9 ± 16.2 | 162.1 ± 16.4 | 231.9 ± 77.8 | 246.5 ± 60.5 | 215.2 ± 30.9 |
| Fasting glucose (mg/dL) |
265.9 ± 21.8 | 262.7 ± 65.8 | 259.6 ± 51.8 | 280.5 ± 92.3 | 265.1 ± 46.8 |
Results represent fasting body weights and plasma values at time of sacrifice. Data is from n = 6–12 mice/group and represents mean ± SD. Statistical analysis was performed using one-way ANOVA and the null hypothesis was rejected for p < 0.05. ∗Significant compared to Rag controls (p < 0.01). #Significant compared to CD8+STAT4+/+ mice (p < 0.05).