Table 5.
12-month NPI results. In the first and third rows it has been reported the within group comparison with baseline and with 6-month results.
| Subitems NPI | Number of patients/48 (%) within groups (12 months versus baseline) (12 months versus 6 months) |
Frequency × severity | Caregiver distress within groups (12 months versus baseline) (12 months versus 6 months) |
|---|---|---|---|
| Hallucinations | 15 (31%) (p < 0.001) (NS) |
2 | 1 (NS) (NS) |
|
| |||
| Delusions | 8 (17%) (p < 0.05) (NS) |
1 | 1 (NS) (NS) |
|
| |||
| Agitation/aggression | 3 (8%) (NS) (NS) |
2 | 1 (NS) (NS) |
|
| |||
| Dysphoria/depression | 19 (40%) (p < 0.05) (NS) |
3 | 1 (p < 0.05) (NS) |
|
| |||
| Anxiety | 21 (44%) (p < 0.001) (NS) |
4 | 1 (p < 0.05) (NS) |
|
| |||
| Irritability | 1 (2%) (p < 0.001) (p < 0.001) |
3 | 1 (p < 0.05) (NS) |
|
| |||
| Disinhibition | 0 (0%) (p < 0.001) (p < 0.001) |
0 | 1 (p < 0.05) (NS) |
|
| |||
| Euphoria | 0 (0%) (p < 0.001) (p < 0.001) |
0 | 1 (p < 0.05) (NS) |
|
| |||
| Apathy | 33 (69%) (p < 0.05) (NS) |
8 | 8 (NS) (NS) |
|
| |||
| Aberrant motor behavior | 1 (4%) (NS) (NS) |
1 | 1 (p < 0.05) (NS) |
|
| |||
| Sleep behavior change | 5 (10%) (p < 0.001) (NS) |
3 | 2 (p < 0.05) (NS) |
|
| |||
| Appetite change | 1 (2%) (p < 0.001) (NS) |
1 | 1 (p < 0.05) (NS) |