Table 3.
Change in Lipid and Nutritional Variables With LVAD Implantation
Variable | At Baseline (±30 d) of LVAD Implantation | At 3 mo (±30 d) Post-LVAD Implantation | No. of Paired Comparisons | Median Change From Baseline to 3 mo | P Value for Baseline to 3-mo Comparison |
---|---|---|---|---|---|
Total cholesterol, mg/dL | 125 (101, 151) | 150 (125, 179) | 129 | 22 (−3, 64) | <0.001 |
LDL, mg/dL | 67 (50, 92) | 85 (51,109) | 63 | 12 (−7, 37) | 0.01 |
HDL, mg/dL | 32 (25, 39) | 42 (35, 50) | 67 | 9 (1, 22) | <0.001 |
Triglycerides, mg/dL | 97 (71, 134) | 126 (89, 170) | 75 | 28 (−13, 62) | <0.001 |
Albumin, g/dL | 3.4 (2.9, 3.8) | 4.0 (3.5, 4.3) | 286 | 0.5 (0, 1.0) | <0.001 |
Values expressed as medians (25th, 75th percentile). Baseline-3 mo comparisons made with Wilcoxon matched-pairs signed-rank tests. HDL indicates high-density lipoprotein; LVAD, left ventricular assist device; and LDL, low-density lipoprotein.