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. Author manuscript; available in PMC: 2017 Apr 2.
Published in final edited form as: Circ Heart Fail. 2016 Sep;9(9):e002881. doi: 10.1161/CIRCHEARTFAILURE.115.002881

Table 4.

Baseline Characteristics of Patients by Total Cholesterol Recovery Status at 3 Months Post-LVAD Implantation

Variable No Cholesterol Recovery* at 3 mo (n=64) Cholesterol Recovery* at 3 mo (n=65) P Value
Female sex       7 (11%)     13 (20%)   0.22
Age, y     62 (51, 69)     53 (46, 61)   0.001
HMII device     57 (89%)     61 (94%)   0.36
Implanted with BTT strategy     38 (59%)     50 (77%)   0.04
BMI, kg/m2  26.2 (22.8, 31.0)  25.3 (22.1, 29.9)   0.67
Baseline statin     36 (56%)     35 (54%)   0.86
Ischemic HF cause     40 (63%)     24 (37%)   0.005
Smoking history     40 (63%)     33 (51%)   0.21
Hypertension history     36 (56%)     37 (57%)   1.0
Diabetes mellitus history     29 (45%)     25 (38%)   0.48
Creatinine, mg/dL    1.4 (1.1, 1.8)    1.3 (1.0, 1.7)   0.41
Hemoglobin, g/dL  10.0 (9.1, 12.2)    9.9 (8.6, 11.9)   0.58
Platelets, 109/L   183 (132, 243)   178 (127, 240)   0.76
Sodium, mmol/L   135 (133, 137)   134 (131, 137)   0.19
Albumin, g/dL    3.3 (2.9, 3.8)    3.3 (2.8, 3.7)   0.64
Total bilirubin, mg/dL    1.3 (0.7, 2.1)    1.4 (0.9, 2.7)   0.22
ALT, U/L     23 (17, 34)     24 (17, 46)   0.40
AST, U/L     34 (21, 58)     38 (25, 65)   0.29
Total cholesterol, mg/dL   137 (113, 167)   109 (94, 127) <0.001
LDL, mg/dL     68 (49, 119)     62 (45, 72)   0.03
HDL, mg/dL     35 (29, 47)     27 (21, 37)   0.01
Triglycerides, mg/dL   103 (77, 175)     89 (72, 113)   0.04
BNP, pg/mL 1080 (377, 2043) 1296 (787, 2277)   0.38
HbA1c, %    6.3 (5.8, 7.6)    6.3 (5.9, 6.8)   0.71
LVEF, %  17.5 (13, 20)     15 (12, 20)   0.04
Duration of LVAD support, d   419 (216, 882)   427 (253, 840)   0.84
Cardiac Transplanation     28 (44%)     34 (52%)   0.38
Mortality during LVAD support     24 (38%)     10 (15%)   0.005
Mortality during or after LVAD support     30 (47%)     12 (18%) <0.001

Values expressed as median (25th, 75th percentiles) or value (percentage of group). Wilcoxon–Mann–Whitney tests for continuations variables and Fisher exact tests for categorical variables. ALT indicates alanine transaminase; AST, aspartate transaminase; BMI, body mass index; BNP, brain natriuretic peptide; BTT, bridge to transplantation; CAD, coronary artery disease; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; HMII, Heartmate II; LDL, low-density lipoprotein; LVAD, left ventricular assist device; and LVEF, left ventricular ejection fraction.

*

Recovery defined as change from baseline to 3 mo post implantation ≥median change.