Table 5.
Unadjusted Hazard Ratio Estimates for All-Cause Mortality for Each Lipid Variable
Baseline (Time 0), per 1 mg/dL/per per Log Unit* for Triglyceride | 3 Mo Post Implantation, per 1 mg/dL/per Log Unit* for Triglyceride | Change From Baseline to 3 Mo Post Implantation, per 1 mg/dL/per Log Unit* for Triglyceride | Recovery† (Binary Variable) at 3 Mo Post Implantation | |
---|---|---|---|---|
Cholesterol unadjusted mortality hazard ratios (95% confidence interval) | 0.998 (0.991–1.004) | 0.983‡ (0.973–0.993) | 0.993§ (0.986–0.999) | 0.445§ (0.212–0.932) |
No. of subjects, No. of events | n=255, events=51 | n=134, events=34 | n=129, events=34 | n=129, events=34 |
LDL unadjusted mortality hazard ratios (95% confidence interval) | 0.995 (0.986–1.004) | 0.971‡ (0.954–0.989) | 0.983 (0.966–1.001) | 0.549 (0.179–1.684) |
No. of subjects, No. of events | n=208, events=39 | n=80, events=16 | n=63, events=13 | n=63, events=13 |
HDL unadjusted mortality hazard ratios (95% confidence interval) | 1.013 (0.990–1.036) | 0.969 (0.931–1.009) | 0.980 (0.952–1.009) | 0.853 (0.299–2.437) |
No. of subjects, No. of events | n=210, events=39 | n=84, events=17 | n=67, events=14 | n=67, events=14 |
Triglyceride unadjusted mortality hazard ratios (95% confidence interval) | 0.751 (0.398–1.417) | 0.672 (0.264–1.711) | 0.532 (0.186–1.525) | 0.282§ (0.089–0.890) |
No. of subjects, No. of events | n=227, events=41 | n=86, events=17 | n=75, events=15 | n=75, events=15 |
Time 0=date of left ventricular assist device implantation. LDL indicates low-density lipoprotein; and HDL, high-density lipoprotein.
Triglyceride log transformed because of positive skew.
Recovery’ defined as change from baseline to 3 mo post implantation ≥median change.
P≤0.01;
P≤0.05.