Table 7.
Headache Impact Test total scores by group at six and 12 months.
| Group | HIT-6 score | St Dev | HIT-6 improvement | P value | 
|---|---|---|---|---|
| ACZ to open-label ACZ | 51.70 | 8.52 | ||
| 50.80 | 9.26 | −0.90 | 0.63 | |
| PLB to open-label ACZ | 53.26 | 9.31 | ||
| 49.56 | 9.40 | −3.70 | 0.01 | |
| ACZ tapered off ACZ | 46.63 | 7.80 | ||
| 45.06 | 10.62 | −1.56 | 0.56 | |
| PLB to no ACZ | 47.82 | 7.37 | ||
| 48.45 | 6.33 | 0.64 | 0.74 | 
ACZ = acetazolamide, PLB = placebo, HIT-6 = Headache Impact Test