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. 2017 Mar 20;11(2):121–129. doi: 10.4162/nrp.2017.11.2.121

Fig. 2. Effects of dietary leucine supplementation on the hepatic mRNA expressions related to mitochondrial biogenesis and energy metabolism in normal birth weight and intrauterine growth-retarded weanling piglets.

Fig. 2

(A) Relative mRNA expressions of SIRT1, PGC-1α, NRF1, TFAM, NDUFA1, NDUFA13, and NDUFB1. (B) Relative mRNA expressions of SDHA, SDHB, COX I, COX IV, COX V, ATP5G1, and ATP5B. NBW-CON, normal birth weight group given a control diet; NBW-LEU, normal birth weight group given a leucine-supplemented diet; IUGR-CON, intrauterine growth-retarded group given a control diet; IUGR-LEU, intrauterine growth-retarded group given a leucine-supplemented diet; BW, birth weight; SIRT1, sirtuin 1; PGC-1α, peroxisome proliferator-activated receptor-γ coactivator 1α; NRF1, nuclear respiratory factor 1; TFAM, mitochondrial transcription factor A; NDUFA1, NADH dehydrogenase 1α subcomplex, 1; NDUFA13, NADH dehydrogenase 1α subcomplex, 13; NDUFB1, NADH dehydrogenase 1β subcomplex, 1; SDHA, succinate dehydrogenase complex, subunit A; SDHB, succinate dehydrogenase complex, subunit B; COX I, cytochrome c oxidase subunit I; COX IV, cytochrome c oxidase subunit IV; COX V, cytochrome c oxidase subunit V; ATP5G1, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1; ATP5B, ATP synthase, H+ transporting, mitochondrial F1 complex, β polypeptide. Data are presented as means ± SEM (n = 8/group). Mean values in columns with unlike superscript letters were significantly different (P < 0.05).