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. 2017 Apr 3;10:90. doi: 10.3389/fnmol.2017.00090

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Copyright © 2017 Noristani, Gerber, Sabourin, Le Corre, Lonjon, Mestre-Frances, Hirbec and Perrin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Induction of DNA damage pathway genes in microglia after SCI. Gene ontology pathway map analysis displaying the induction of DNA damage pathway in microglia after SCI (A). Thermometers indicate deregulated transcripts (red, up-regulated; blue, down-regulated). Interactions between objects, green (positive or activation); red (negative or inhibition); gray (unspecified); B: Binding (physical interaction between molecules); Binding protein, Kinase, Generic enzyme. Bar graphs displaying over-expression of transcripts involved in DNA damage pathway at different time-points after HS and FT injuries (B–I). Values are actual fold change, t-test between HS and FT at a given time point (^*p < 0.05; ^***p < 0.001).

Inline graphic — Induction of DNA damage pathway genes in microglia after SCI. Gene ontology pathway map analysis displaying the induction of DNA damage pathway in microglia after SCI (A). Thermometers indicate deregulated transcripts (red, up-regulated; blue, down-regulated). Interactions between objects, green (positive or activation); red (negative or inhibition); gray (unspecified); B: Binding (physical interaction between molecules); Binding protein, Kinase, Generic enzyme. Bar graphs displaying over-expression of transcripts involved in DNA damage pathway at different time-points after HS and FT injuries (B–I). Values are actual fold change, t-test between HS and FT at a given time point (^*p < 0.05; ^***p < 0.001).