Fig. 4.

Effects of coapplied DIDS and furosemide and of S0859 on the fiber volley. A1: normalized fiber volley amplitude and latency recorded during washin of furosemide (2.5 mM, n = 5), DIDS (0.5 mM, n = 9), or the 2 drugs combined (n = 5). A2: fiber volley amplitude as function of stimulus number (normalized to stimulus 1) in HFS trains of 100 Hz before (control) and after 45-min perfusion of DIDS + furosemide. A3: summary histograms comparing amplitude (top) and area (bottom) of near-maximally enhanced fiber volleys (stimulus 10 at 100 Hz; stimulus 20 at 20 Hz) and of the volleys evoked at stimulus 100 from the control period (filled bars) and in the presence of DIDS + furosemide (open bars) B: plots as in A but recorded with perfusion of S0859 (30 µM). *P < 0.05; **P < 0.01.