Table 1.

Effects of anion transport inhibitors, sucrose, and ZD7288 on evoked fiber volleys in stratum radiatum and alveus of CA1

		Drug Effect on Fiber Volley
	n	Amplitude	Area	Latency
Furosemide (2.5 mM, 30 min)	9	79 ± 6%**	84 ± 6%*	110 ± 2%**
Furosemide (2.5 mM, 30 min) with gabazine	6	81 ± 4%**	84 ± 4%*	109 ± 2%*
Bumetanide (20 µM, 30 min)	7	96 ± 2%	98 ± 4%	100 ± 2%
VU0240551(20 µM, 30 min)	5	108 ± 6%	99 ± 2%	98 ± 2%
DIDS (0.5 mM, 45 min)	9	80 ± 5%**	90 ± 6%	113 ± 3%**
DIDS + furosemide (45 min)	5	55 ± 6%*	74 ± 7%*	124 ± 2%**
S0859 (30 µM, 45 min)	7	102 ± 1%	102 ± 5%	101 ± 2%
Sucrose (30 mM, 30 min)	6	89 ± 4%	93 ± 4%	97 ± 1%*
ZD7288 (20 µM, 30 min)	11	100 ± 4%	101 ± 4%	101 ± 2%
Furosemide (2.5 mM, 30 min) with ZD7288	7	76 ± 4%**	83 ± 5%*	113 ± 2%**
Alveus, furosemide (2.5 mM, 30 min)	11	66 ± 4%**	74 ± 4%**	128 ± 3%**
Alveus, bumetanide (20–50 µM, 30 min)	9	100 ± 1%	103 ± 4%	103 ± 1%**

Percentages (means ± SE) are relative to control before drug application. All data were collected in the presence of CNQX (20–40 µM), MK 801 (10 µM), and CGP55845 (2 µM).

^*P < 0.05;

^**P < 0.01.