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. 2017 Apr 3;16:73. doi: 10.1186/s12943-017-0642-7

Fig. 2.

Fig. 2

Gene and cell-to-cell correlation analysis. a Heatmap (unsupervised clustering, Euclidian distance) demonstrating gene correlations coefficients (Spearman) based on gene expression of all cells. b Heatmap (unsupervised clustering, Euclidian distance) demonstrating cell-to-cell correlations coefficients (Spearman) based on individual gene expression profile of each cell. Manual grouping was performed according to hierarchical clustering to obtain five subgroups