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. 2017 Mar 7;9(4):531–544. doi: 10.15252/emmm.201607231

Figure EV4. Full immunoblots from AAV8.Mstn‐ and AAV8.GDF11‐treated mice.

Figure EV4

  • A, B
    Quadriceps (A) and heart (B) lysates from mice described in Figs 2 and EV2 were immunoblotted for phosphorylated and total content of SMAD3, SMAD1/5/8, Akt, p38 MAPK, ERK1/2, total SMAD4, and total NOX4. GAPDH content was used as a loading control and normalization standard. Note that the cropped version of many of these images is found in Fig 5A and B.
  • C
    Phosphorylation of TAK1 is not different between control and AAV8.GDF11‐treated hearts or quadriceps.