Table 2.
List of biomarkers used in the transcriptomic signature
| Gene symbol | Affymetrix ID | RefSeq | mRNA_assignment | |
|---|---|---|---|---|
| Upregulated transcripts in MYC‐high cohort | CDC20 | 16663514 | NM_001255 | Homo sapiens cell division cycle 20 |
| KPNA2 | 16837270 | NM_002266 | Homo sapiens karyopherin alpha 2 | |
| PLK1 | 16817017 | ENST00000300093 | Homo sapiens polo‐like kinase 1 | |
| SRM | 16681611 | NM_003132 | Homo sapiens spermidine synthase | |
| RFC4 | 16962493 | NM_002916 | Homo sapiens replication factor C (activator 1) 4 | |
| MCM2 | 16945101 | ENST00000265056 | Homo sapiens minichromosome maintenance complex component 2 | |
| RUVBL2 | 16863946 | NM_006666 | Homo sapiens RuvB‐like 2 (E. coli) | |
| MAD2L1 | 16979389 | ENST00000296509 | Homo sapiens MAD2 mitotic arrest deficient‐like 1 | |
| CCT4 | 16898175 | NM_006430 | Homo sapiens chaperonin containing TCP1, subunit 4 (delta) | |
| CAD | 16878137 | NM_004341 | Homo sapiens carbamoyl‐phosphate synthetase 2 | |
| Downregulated transcripts in MYC‐high cohort | VSIG2 | 16745683 | NM_014312 | Homo sapiens V‐set and immunoglobulin domain containing 2 |
| BCL2L15 | 16691121 | NM_001010922 | Homo sapiens BCL2‐like 15 (BCL2L15) | |
| RAB25 | 16671901 | NM_020387 | Homo sapiens RAB25, member RAS oncogene family | |
| TXNIP | 16669796 | NM_006472 | Homo sapiens thioredoxin interacting protein | |
| CTSE | 16676547 | NM_001910 | Homo sapiens cathepsin E, transcript variant 1 | |
| ERN2 | 16825120 | NM_033266 | Homo sapiens endoplasmic reticulum to nucleus signaling 2 |