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. 2017 Feb 20;9(4):415–429. doi: 10.15252/emmm.201606937

Figure 4. Inhibition of SK4 channels by 2 μM TRAM‐34 lessens the arrhythmic phenotype of SAN cells from CASQ2‐D307H KI mice.

Figure 4

  1. Representative traces of spontaneous APs recorded in a SAN cell from WT mice under the indicated conditions.
  2. Histograms of statistical data of the beating rate, DD slope, and MDP of SAN cells from WT mice. One‐way ANOVA followed by Tukey's multiple comparison test. For rate, *P <  0.05, n = 6; for DD slope, *P < 0.05, **P < 0.01, n = 7; for MDP, *P < 0.05, n = 5. Bars and error bards are mean ± SEM.
  3. Representative traces of spontaneous APs recorded in a SAN cell from CASQ2‐D307H KI mice under the indicated conditions.
  4. Histograms of statistical data of the beating rate, and MDP of SAN cells from CASQ2‐D307H KI mice. One‐way ANOVA followed by Tukey's multiple comparison test. For the rate, P is not significant, n = 5; for DADs, **P < 0.01, n = 5. Bars and error bards are mean ± SEM.