Table 1.
Number of mice (n) | 5 | 5 | 12 | 12 |
---|---|---|---|---|
Vehicle | Clotrimazole 20 mg/kg | Vehicle | TRAM‐34 20 mg/kg | |
KI at rest | ||||
Normal | 0 | 3 | 3 | 9 |
VPC | 4 | 2 | 6 | 3 |
NSVT | 1 | 0 | 3 | 0 |
SVT | 0 | 0 | 0 | 0 |
KI during exercise | ||||
Normal | 0 | 0 | 1 | 4 |
VPC | 1 | 2 | 2 | 4 |
NSVT | 4 | 2 | 9 | 4 |
SVT | 0 | 1 | 0 | 0 |
Number of mice (n) | 6 | 6 | 6 | 6 |
---|---|---|---|---|
Vehicle | Clotrimazole 20 mg/kg | Vehicle | TRAM‐34 20 mg/kg | |
KO at rest | ||||
Normal | 0 | 4 | 1 | 6 |
VPC | 4 | 2 | 5 | 0 |
NSVT | 2 | 0 | 0 | 0 |
SVT | 0 | 0 | 0 | 0 |
KO during exercise | ||||
Normal | 0 | 0 | 0 | 3 |
VPC | 0 | 2 | 0 | 0 |
NSVT | 5 | 3 | 3 | 3 |
SVT | 1 | 1 | 3 | 0 |
VPC, ventricular premature complexes; NSVT, non‐sustained ventricular tachycardia; SVT, sustained ventricular tachycardia. The types of arrhythmic features were classified following their severity: sinusal rhythm (normal), ventricular premature contractions (VPC), NSVT, and SVT.