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. 2017 Feb 20;18(4):569–585. doi: 10.15252/embr.201643068

Figure 6. Summary of miR18a‐dependent regulation of GSH metabolism in MYC‐driven murine liver tumors.

Figure 6

MYC suppresses GCLC via miR‐18a. Attenuated GCLC contributes to GSH depletion. Relative flux of glutamine‐derived carbons to other downstream pathways, such as the TCA cycle and protein synthesis, remains to be determined (dotted line).