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. 2017 Feb 1;11(2):PC01–PC05. doi: 10.7860/JCDR/2017/25473.9251

[Table/Fig-3]:

Sensitivity, specificity, positive and negative predictive values at various PSA/PSAD cut offs as well as for suspicious DRE in different PSA ranges.

Observation Sensitivity (%) Specificity (%) Positive Predictive Value (%) Negative Predictive Value (%)
Suspicious DRE
• Overall
• PSA 4 – 10
• PSA 10 – 20
• PSA 20 – 30
• PSA 30 – 50
• PSA 50 – 100
• PSA > 100

62.32
60
40
71.43
100
70
83.33

89.75
89.87
93.94
80
66.67
-
-

71.67
27.27
50
62.5
60
100
100

85.14
97.26
91.18
85.71
100
-
-
PSA Cut offs
• 4 ng/ml
• 10 ng/ml
• 20 ng/ml
• 30 ng/ml
• 50 ng/ml
• 100 ng/ml

98.33
90
73.33
61.67
56.67
40

5.14
50.28
88
96.57
100
100

26.22
38.3
67.69
86.04
100
100

90
93.62
90.59
88.02
87.06
82.94
PSA Density Cut offs
• 0.05 ng/ml/cm3
• 0.1 ng/ml/cm3
• 0.15 ng/ml/cm3
• 0.2 ng/ml/cm3
• 0.25 ng/ml/cm3

98.33
96.67
93.33
88.33
86.67

6.29
20.57
45.71
61.14
70.29

26.46
29.44
37.08
43.8
50

91.67
94.74
95.24
93.86
93.89