[Table/Fig-7]:
Distribution of VDR haplotypes by clinical group and their association with the risk of chronic periodontitis.
| Haplotype* | Clinical groups† | OR (95%CI)§ | p-value|| | |
|---|---|---|---|---|
| Healthy controls‡ (n = 97) |
Chronic periodontitis‡ (n = 206) |
|||
| GGTT | 22 (22.68) | 59 (28.64) | Referent | |
| GGCT | 13 (13.40) | 40 (19.42) | 0.69 (0.21 - 2.25) | 0.540 |
| TACC | 26 (26.80) | 50 (24.27) | 0.56 (0.23 - 1.35) | 0.200 |
| TGCT | 14 (14.43) | 31 (15.05) | 0.58 (0.20 - 1.69) | 0.320 |
| TATC | 7 (7.22) | 9 (4.37) | 0.36 (0.11 - 1.25) | 0.110 |
| TACT | 6 (6.19) | 10 (4.85) | 0.61 (0.19 - 1.98) | 0.410 |
| TGTT | 9 (9.28) | 7 (3.40) | 0.17 (0.03 - 0.95) | 0.045 |
* The order of the polymorphism is as follows: rs7975232, rs1544410, rs2228570, and rs731236
† Values are given as n (%) of haplotypes within diagnosis
‡ Six haplotypes with a total frequency of <5% were excluded from analysis: 3 HC and 14 CP cases
§ Odds ratio (95% confidence interval)
|| Two-sided Pearson’s chi-square test (χ2)