Table 2. Alterations in IGA and EASI scores and area of lesion to BSA (*: 95% confidence interval) measured until week 24.
Pimecrolimus | Desonide | p-value | |
---|---|---|---|
IGA score at week 1 | 2.9 (2.4–3.2)* | 2.4 (2.0–2.9) | 0.146 |
IGA score at week 2 | 2.5 (1.9–3.0) | 2.0 (1.6–2.5) | 0.185 |
IGA score at week 4 or open | 2.4 (1.8–3.1) | 2.1 (1.6–2.6) | 0.346 |
IGA score at week 24, open-label phase | 1.5 (1.0–2.0) | 1.6 (1.3–2.0) | 0.641 |
EASI score at week 1 | 8.3 (6.3–10.3) | 5.1 (3.9–6.3) | 0.007 |
EASI score at week 2 | 6.3 (4.4–8.1) | 3.0 (2.1–4.0) | 0.003 |
EASI score at week 4 or open | 7.0 (4.4–9.6) | 3.5 (2.1–4.0) | 0.016 |
EASI score at week 24, open-label phase | 3.1 (1.7–4.6) | 2.3 (1.4–3.3) | 0.340 |
Area of lesion to BSA at week 1; % | 19.4 (15.0–23.8) | 14.8 (10.9–18.8) | 0.118 |
Area of lesion to BSA at week 2; % | 13.7 (9.3–18.1) | 9.1 (5.8–12.5) | 0.097 |
Area of lesion to BSA at week 4 or open; % | 13.6 (8.3–18.8) | 8.7 (6.1–11.3) | 0.093 |
Area of lesion to BSA at week 24, open-label phase; % | 5.4 (3.2–7.6) | 5.6 (2.8–8.5) | 0.906 |
IGA: Investigator's Global Assessment total eosinophil;
EASI: Eczema Area and Severity Index;
BSA: Body Surface Area.