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. 2017 Jan 31;13(4):1353–1359. doi: 10.3892/etm.2017.4093

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effects of different concentrations of isoquercetin on primary cultures of rat hippocampal neurons after OGD/R. (A) Cell viability was determined by MTT assay, and (B) LDH release and (C) ROS levels were measured. Data are shown as the mean ± standard error of the mean (n=6). *P<0.05, **P<0.01 and ***P<0.001 vs. the OGD/R group; ^###P<0.001 vs. the control group. OGD/R, oxygen-glucose deprivation followed by reoxygenation; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; LDH, lactate dehydrogenase; ROS, reactive oxygen species; OD, optical density.