Table 1. Potential cost savings from using the paper-based SCD newborn screening test as a preliminary screen, followed by confirmatory diagnosis of only screened-in HbS-positive newborns via isoelectric focusing (IEF).

	IEF alone	Paper-based test + IEF
Cohort size	159	159
Number screened by paper-based test	0	159
Total cost of paper-based screening (at $2.16/test)	$0	$343.44
Number requiring IEF testing	159	48
Total cost of IEF testing (at $4.94/test)	$785.46	$237.12
Total cost of all testing	$785.46	$580.56
Average cost per sample	$4.94	$3.65