Figure 2.

ICA treatment increases BMD. After 12 weeks of treatment, mice were anesthetized and whole body scans were conducted. BMD of the whole body, femora and tibias, as well as the fourth and fifth lumbar vertebrae, were measured. *P<0.05, **P<0.01 vs. the sham-operated group; ^∆P<0.05, ^∆∆P<0.01 vs. the OVX-NT group. BMD, bone mineral density; OVX-NT, ovariectomized-no treatment group; ICA-L, low-dose icariin group; ICA-M, medium-dose icariin group; ICA-H, high-dose icarrin group; FOS, Fosamax-treated positive control group; LV, lumbar vertebrae.